In this video you will hear testimonial of patients stem cell therapy for knee carrtilage and the results of ACL repair.
With the development of Osteoarthritis, a distinct change in the joint environment occurs. Chondrocytes begin to elaborate destructive enzymes causing cracks and fissures in the cartilage. These are called “fibrillations.” A complex interplay of events involving cartilage, bone, and synovium- the lining of the joint- then begins to snowball.
One of the most common joints affected by osteoarthritis is the knee. This is not a surprise since OA preferentially attacks weight-bearing joints.
Combining MSCs with autologous growth factors found in platelet-rich plasma also has added a boost to the natural abilities of stem cells to multiply and divide.
Stem cells are pluripotential cells, meaning they are cells that can become any kind of tissue, given the right stimulus. Stem cells can be obtained from embryonic tissue, which is a source of much controversy.
Or they can be obtained from adults. The adult body has a small number of stem cells in many tissues. They are activated by injury or illness. Adult stem cells, as a rule, do not have the ability to differentiate as well as embryonic stem cells.
After the stem cells are prepared, the physician, using ultrasound guidance and local anesthetic, finds the area of arthritis involvement and irritates the area using a special large needle. This irritation is important because it initiates an inflammatory reaction which is the prelude to healing and regeneration. The areas that are irritated include the capsule, tendon insertions, pericapsular soft tissue, as well as cartilage.
Blood is drawn from the patient and spun in a special centrifuge in order to obtain platelet rich plasma. Platelets are blood cells that contain multiple growth and healing factors.
Once the irritation has been completed, stem cells as well as the platelet rich plasma are injected into the prepared area.
The growth factors within the platelet rich plasma act on receptors found on the surface of stem cells and cause the stem cells to differentiate and multiply.
The end result is cartilage regeneration as well as lessening of pain.
To know more about stem cell knee cartiage regeneration and acl repair, please contact us.