The amyotrophic lateral sclerosis (ALS) is a progressive degeneration in nerve cells (which control your striated muscles) located in the brain and spinal cord. The affected neurons atrophy and disappear without showing any signs of abnormalities. Then, the muscles get damaged due to the disappearance of the needs in charge of stimulating these muscles.
The onset of the disease is gradual. Typically, there is an increase in muscle weakness of an extremity, especially in the patients’ hands. Then, other extremities can be affected. This weakness may be accompanied by muscle spasms and cramps. As the disease progresses, new muscles are affected and, in the end, a total paralysis occurs.
Stem cells have a regenerative capacity and are able to transform different types of cells. The stem cell therapy replenishes the motor neurons stores and other cells in order to protect motor neurons and to restore the microenvironment within the brain and the spinal cord.
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